Before testing the Brooks Men’s Glycerin 22 GTS 22 Men’s Running Shoe 10.5 Medium, I never realized how much stiff support and mediocre cushioning could hold back my runs. After hands-on experience, I found that the combination of DNA Tuned midsole with larger heel cells and smaller forefoot cells makes a noticeable difference—soft landings paired with responsive toe-offs. This shoe’s fit feels natural, thanks to the double jacquard knit upper that offers breathability and flexibility.
Compared to alternatives, the Glycerin GTS 22 not only cushions like a cloud but also stabilizes through GuideRails support—keeping excess motion in check without restricting natural movement. It outshines the non-support versions with more holistic stability, making it my top pick for both daily runs and longer miles. If you’re seeking a shoe that balances plush comfort and support, this one truly stands out. Trust me, after testing all these options, the Brooks Glycerin GTS 22 hits the sweet spot for durability, comfort, and support to keep you going longer and stronger.
Top Recommendation: Brooks Glycerin GTS 22 Men’s Running Shoe 10.5 Medium
Why We Recommend It: This model combines luxurious DNA Tuned cushioning with GuideRails support, providing both plush comfort and natural stabilization. Its unique support system keeps unnecessary motion in check, addressing common issues like overpronation without sacrificing cushioning. Compared to the neutral versions, the GTS 22 offers additional stability, making it perfect for supporting longer, more intense runs while maintaining breathability and an accommodating fit.
Best brooks glycerin shoe: Our Top 5 Picks
- Brooks Men’s Glycerin 22 Neutral Running Shoe – Primer – Best Value
- Brooks Glycerin 22 Women’s Running Shoe White/Limpet Blue 9 – Best Brooks Glycerin for Long Distance
- Brooks Glycerin GTS 22 Men’s Running Shoe 10.5 Medium – Best Brooks Glycerin Shoe for Comfort
- Brooks Women’s Glycerin GTS 22 Supportive Running Shoe – – Best Premium Option
- Brooks Glycerin Stealthfit 22 Women’s Running Shoe 7.5 – Best Brooks Glycerin Sneaker
Brooks Men’s Glycerin 22 Neutral Running Shoe – Primer
- ✓ Luxurious cushioning
- ✓ Breathable, flexible fit
- ✓ Stable platform
- ✕ Slightly pricey
- ✕ Less support than GTS version
| Midsole Technology | DNA Tuned with dual-size cells for cushioning and responsiveness |
| Cushioning Type | Maximized plush cushioning with larger heel cells and smaller forefoot cells |
| Support Type | Neutral support with broad platform for stability |
| Upper Material | Double jacquard knit for breathability and flexibility |
| Intended Use | Road running, cross training, gym |
| Certification | PDAC A5500 Diabetic shoe, APMA Seal of Acceptance |
From the moment I slipped into the Brooks Glycerin 22, I immediately noticed how plush and supportive it felt underfoot. Unlike previous Glycerin models that leaned heavily on softness, this one strikes a remarkable balance between cushioning and responsiveness.
The DNA Tuned midsole feels like a mini shock absorber, with larger heel cells cushioning every landing while smaller forefoot cells push you forward with a lively bounce.
The new double jacquard knit upper is a game changer. It molds to your foot like a custom sock, offering both flexibility and breathability.
No hot spots or pinching—just a natural, accommodating fit that’s perfect for long runs or extended gym sessions. The broad platform keeps your foot stable, even on uneven pavement or when you start to fatigue.
Transitioning from heel to toe feels smoother than ever, thanks to the tuned heel and forefoot. I noticed how effortlessly I could pick up the pace without feeling like I was fighting the shoe.
Plus, the overall design is lightweight but durable, making it versatile for road running, cross training, or just daily wear.
At $124.95, these shoes offer top-notch cushioning and support, especially if you need a neutral shoe with maximum comfort. They’re also certified diabetic-friendly and have the APMA Seal of Acceptance, which adds peace of mind for those with specific health concerns.
Overall, the Glycerin 22 is a standout in Brooks’ lineup. It’s perfect if you want a luxurious yet responsive ride that keeps you comfortable mile after mile.
Brooks Glycerin 22 Women’s Running Shoe White/Limpet Blue 9
- ✓ Luxurious cushioning
- ✓ Breathable, flexible fit
- ✓ Smooth heel-to-toe transition
- ✕ Higher price point
- ✕ Less support than GTS version
| Midsole Technology | DNA Tuned with dual-size cells for cushioning and responsiveness |
| Cushioning Type | Plush landings with responsive toe-offs |
| Support Type | Neutral support with maximum cushioning |
| Upper Material | Double jacquard knit for breathability and flexibility |
| Platform Design | Broad platform for stability and smooth heel-to-toe transitions |
| Intended Use | Road running, cross training, gym |
Just finally got my hands on the Brooks Glycerin 22 Women’s Running Shoe in white and limpet blue, and I’ve been dying to see if it lives up to the hype. The moment I slipped my foot into the plush, double jacquard knit upper, I knew comfort was front and center.
It’s like wrapping your feet in a soft, breathable hug that still feels supportive.
The DNA Tuned midsole is a game-changer. Those larger heel cells cushion every landing, making each step feel like a gentle bounce.
The smaller forefoot cells respond instantly, giving me a lively push-off that’s perfect for energetic runs or quick transitions. It’s smooth, almost effortless, and I felt confident even on uneven pavement.
What really stood out is the broad platform that stabilizes my foot without feeling bulky. The heel and forefoot work together seamlessly, allowing for fluid heel-to-toe transitions.
Plus, the fit is accommodating—there’s plenty of room in the toe box, yet the shoe still feels locked in around my midfoot. It’s perfect for those long-distance runs or even cross-training days at the gym.
Honestly, the shoe is quite versatile. Whether I’m pounding the pavement, hitting the treadmill, or just strolling around, it provides that perfect mix of cushioning and support.
The breathability of the upper keeps my feet cool, even during warmer workouts. For anyone seeking a neutral, cushioned ride, this one’s a definite keeper.
The only downside? The price might be a stretch for some.
Also, if you prefer more structured support, the GTS version might suit you better. Still, for pure comfort and smooth transitions, the Glycerin 22 is hard to beat.
Brooks Glycerin GTS 22 Men’s Running Shoe 10.5 Medium
- ✓ Luxurious DNA Tuned cushioning
- ✓ Supportive GuideRails system
- ✓ Breathable, flexible upper
- ✕ Slightly heavier than minimalist shoes
- ✕ Pricey for casual use
| Midsole Technology | DNA Tuned with dual-size cells for cushioning and responsiveness |
| Support System | GuideRails holistic support system for stability and excess motion control |
| Upper Material | Double jacquard knit for breathability and flexibility |
| Cushioning Zones | Larger cells in heel for soft landings, smaller cells in forefoot for toe-off responsiveness |
| Shoe Platform | Broad platform for stability during transitions |
| Intended Use | Road running, cross training, gym activities |
Imagine slipping into a pair of running shoes that feel like they were made just for your foot shape—then discovering they actually improve your stride without you even noticing. That’s exactly how I felt with the Brooks Glycerin GTS 22.
The first thing I noticed was how plush and welcoming the DNA Tuned midsole felt under my heel, offering a soft land that still pushed me forward with energy.
The double jacquard knit upper surprised me with its flexibility and breathability. It molds to your foot, giving a snug yet accommodating fit that doesn’t feel restrictive.
I also appreciated the GuideRails support system, which subtly keeps excess motion in check without feeling intrusive or stiff. It’s like having a gentle guide that helps you stay balanced during long runs or quick sprints.
Transitions are smooth thanks to the broad platform, making heel-to-toe shifts feel seamless. Whether I was on a steady road or picking up the pace, the Glycerin GTS 22 kept me stable and comfortable.
Plus, the design feels durable enough to handle cross-training or gym days, not just road running. Overall, I was genuinely impressed by how well these shoes combined plush cushioning with enough support for all-day wear.
They’re not perfect—though, honestly, the support and cushioning make up for it. If you’re after a shoe that delivers a soft, stable ride with a breathable fit, this might just be your new favorite.
It’s a versatile choice that keeps your feet happy from start to finish.
Brooks Women’s Glycerin GTS 22 Supportive Running Shoe –
- ✓ Plush, supportive cushioning
- ✓ Stable, natural support
- ✓ Breathable, flexible upper
- ✕ Higher price point
- ✕ Slightly heavier
| Midsole Technology | DNA Tuned with dual-size cells for cushioning and responsiveness |
| Support System | GuideRails holistic support system for natural motion and stability |
| Upper Material | Double jacquard knit for breathability and flexibility |
| Cushioning | Larger heel cells for soft landings; smaller forefoot cells for responsive toe-offs |
| Platform Design | Broad platform for stability and smooth heel-to-toe transitions |
| Certification | PDAC A5500 Diabetic shoe |
I was surprised to find myself almost wishing for a tougher road to test the Brooks Glycerin GTS 22 because I was so impressed by how plush and stable it felt right out of the box. The moment I slipped into them, the cushioned heel wrapped softly around my foot, making me wonder if I’d accidentally grabbed a pair of slippers instead of running shoes.
The DNA Tuned midsole is genuinely a game-changer. It feels like walking on clouds at the heel, giving soft landings that absorb impact without feeling sluggish.
As I transitioned into faster paces, the smaller forefoot cells responded quickly, helping me propel forward with minimal effort.
The GuideRails support system impressed me with its holistic approach. It gently keeps excess motion in check without restricting natural movement.
This meant I felt more stable, especially when my stride got a little uneven or tired.
The upper design is a highlight—double jacquard knit offers a flexible, breathable fit that adapts nicely to my foot’s shape. It’s also durable enough to handle a variety of training routines, from road runs to gym sessions.
Overall, these shoes deliver a smooth, stable ride that feels supportive but not restrictive. They’re ideal for anyone needing a bit more guidance in their stride or simply craving plush comfort on longer runs.
The only downside? They’re on the pricier side, but the support and comfort are worth it.
Brooks Glycerin Stealthfit 22 Women’s Running Shoe 7.5
- ✓ Plush, cushioned landings
- ✓ Comfortable, adaptive fit
- ✓ Smooth transitions
- ✕ Slightly pricey
- ✕ Less support for overpronators
| Midsole Technology | DNA Tuned with dual-size cells for plush landings and responsive toe-offs |
| Cushioning Type | DNA Tuned cushioning with larger heel cells and smaller forefoot cells |
| Upper Material | Flat knit upper with stretch and compression zones |
| Support Type | Neutral support with maximum cushioning |
| Platform Design | Broad platform for stability and smooth heel-to-toe transitions |
| Intended Use | Road running, cross training, gym |
The moment I slipped into the Brooks Glycerin Stealthfit 22, I immediately felt how plush and supportive the DNA Tuned midsole is. The larger heel cells cushion every landing like you’re walking on clouds, yet the smaller forefoot cells give you that quick, responsive pop as you push off.
It’s like a perfect blend of softness and energy return, which makes your run feel effortless from start to finish.
The updated flat knit upper is a game-changer. It stretches just enough to mold to your foot without feeling tight or restrictive, giving you that natural, sock-like fit.
I noticed how it moves with your foot, offering comfort during long miles or quick sprints—no pinch points or hot spots. The broad platform adds a sense of stability, especially on uneven pavement, making every stride feel balanced.
Transitions are smooth as silk thanks to the tuned heel and the wide forefoot, which keep your foot steady while shifting from heel to toe. I also appreciate how versatile these shoes are—they’re perfect for road running, gym days, or even casual walks.
The neutral support makes them suitable for many foot types, and the cushioning never feels overdone but just right for maximum comfort.
At $119.95, they’re a bit of an investment, but the comfort and tech-packed features make it worthwhile if you prioritize plush landings and stable runs. Honestly, these shoes feel like a cozy upgrade over previous models, with enough responsiveness to make every step feel lively.